dihydropyrimidinase D-hydantoinase, 5,6-dihydropyrimidine amidohydrolase; (DHPase) (PA0441)

Identification
Name: dihydropyrimidinase D-hydantoinase, 5,6-dihydropyrimidine amidohydrolase; (DHPase)
Synonyms: hyuA
Gene Name: dht
Enzyme Class: Not Available
Biological Properties
General Function: pyrimidine nucleobase catabolic process
Specific Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Cellular Location: Cytoplasmic
KEGG Pathways:
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    5,6-dihydrouracil + H2O = 3-ureidopropanoate + H+
    ReactionCard
    PAMDB120196+PAMDB000142 → PAMDB120191
    phenylhydantoin + Water → phenylureidoacetic acid
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Component
    cytoplasm
    Function
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    Process
    pyrimidine nucleobase catabolic process
    Gene Properties
    Locus tag: PA0441
    Strand: -
    Entrez Gene ID: 882285
    Accession: NP_249132.1
    GI: 15595638
    Sequence start: 494816
    Sequence End: 496255
    Sequence Length: 1439
    Gene Sequence: 
    >PA0441
ATGTCCCTGTTGATCCGTGGCGCCACCGTGGTTACTCACGAAGAGAGTTATCGAGCCGATGTGCTCTGTGCCAACGGCCTCATCCAGGCCATCGGCGAGAACCTCGAAACCCCCTCCGGCTGCGACGTCCTCGACGGCGGTGGCCAGTACCTGATGCCGGGCGGCATCGACCCCCATACCCACATGCAGTTGCCCTTCATGGGCACGGTGGCCAGCGAGGACTTCTTCAGCGGCACCGCGGCCGGGCTGGCCGGAGGGACCACCTCGATCATCGACTTCGTCATCCCCAACCCGCGACAGTCGCTGCTGGAGGCCTTCCACACCTGGCGCGGCTGGGCGCAGAAATCCGCTGCGGACTACGGCTTCCACGTCGCCATCACCTGGTGGAGCGACGAGGTCGCCCGGGAAATGGGCGAGCTGGTGGCACAGCACGGGGTGAACAGCTTCAAGCACTTCATGGCCTACAAGAACGCCATCATGGCCGCCGACGATACCCTGGTGGCCAGCTTCGAGCGCTGCCTGGAGCTGGGCGCGGTGCCGACGGTGCACGCGGAGAACGGCGAACTGGTCTTCCACCTGCAGCAGAAACTCCTCGCCCAGGGCCTCACCGGCCCCGAGGCGCATCCTCTGTCGCGTCCGCCGCAAGTCGAGGGCGAGGCCGCCAGCCGCGCCATCCGCATAGCCGAGACGCTGGGTACGCCGCTGTACCTGGTACATATTTCCAGCCGCGAGGCGCTGGACGAGATCGCCTATGCCCGCGCCAAGGGCCAGCCGGTCTACGGCGAGGTGCTGGCCGGGCACCTGCTGCTCGACGACAGCGTCTACCGCCACCCGGACTGGGCCACCGCGGCCGGCTACGTGATGAGCCCGCCGTTCCGTCCCGTCGAACACCAGGAAGCGCTGTGGCGCGGCCTGCAGTCCGGCAACCTGCATACCACCGCCACCGACCACTGCTGCTTCTGCGCCGAGCAGAAGGCCATGGGCCGCGACGACTTCAGCAAGATTCCCAATGGCACGGCCGGCATCGAGGACCGCATGGCGCTGCTGTGGGACGCCGGGGTCAACAGCGGGCGCCTGTCGATGCACGAGTTCGTCGCGCTGACCTCCACCAACACCGCGAAGATCTTCAACCTGTTCCCGCGCAAGGGCGCGATCCGCGTCGGCGCGGATGCCGACCTGGTGCTCTGGGACCCGCAGGGCAGCCGCACCCTCTCGGCCGCCACCCACCACCAGCGGGTCGATTTCAACATCTTCGAAGGTCGCACCGTGCGCGGCATTCCCAGCCACACCATCAGCCAGGGCAAGCTGCTCTGGGCCGCCGGCGACCTGCGCGCCGAACCCGGCGCCGGACGCTACGTGGAGCGCCCGGCCTACCCGTCGGTGTACGAAGTGCTCGGCCGCCGCGCCGAACGCCAGCGCCCGGTCGCCGTCGAGCGCTGA
    Protein Properties
    Protein Residues: 479
    Protein Molecular Weight: 52.2 kDa
    Protein Theoretical pI: 6.17
    Hydropathicity (GRAVY score): -0.171
    Charge at pH 7 (predicted): -9.36
    Protein Sequence: 
    >PA0441
MSLLIRGATVVTHEESYRADVLCANGLIQAIGENLETPSGCDVLDGGGQYLMPGGIDPHTHMQLPFMGTVASEDFFSGTAAGLAGGTTSIIDFVIPNPRQSLLEAFHTWRGWAQKSAADYGFHVAITWWSDEVAREMGELVAQHGVNSFKHFMAYKNAIMAADDTLVASFERCLELGAVPTVHAENGELVFHLQQKLLAQGLTGPEAHPLSRPPQVEGEAASRAIRIAETLGTPLYLVHISSREALDEIAYARAKGQPVYGEVLAGHLLLDDSVYRHPDWATAAGYVMSPPFRPVEHQEALWRGLQSGNLHTTATDHCCFCAEQKAMGRDDFSKIPNGTAGIEDRMALLWDAGVNSGRLSMHEFVALTSTNTAKIFNLFPRKGAIRVGADADLVLWDPQGSRTLSAATHHQRVDFNIFEGRTVRGIPSHTISQGKLLWAAGDLRAEPGAGRYVERPAYPSVYEVLGRRAERQRPVAVER
    References
    External Links:
    Resource Link
    Genome ID: PA0441
    Entrez Gene ID: 882285
    NCBI Protein ID: 15595638
    General Reference: PaperBLAST - Find papers about PA0441 and its homologs