Identification
Name: cystathionine beta-synthase methylcysteine synthase; beta-thionase; serine sulfhydrase
Synonyms: Not Available
Gene Name: Not Available
Enzyme Class: Not Available
Biological Properties
General Function: cysteine biosynthetic process from serine
Specific Function: adenyl nucleotide binding
Cellular Location: Cytoplasmic
KEGG Pathways:
  • superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) PWY-821
  • L-cysteine biosynthesis III (from L-homocysteine) HOMOCYSDEGR-PWY
  • L-homocysteine and L-cysteine interconversion PWY-801
  • cysteine biosynthesis III (mammalian) PWY-6292
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    L-homocysteine + L-serine → L-cystathionine + H2O
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    adenyl nucleotide binding
    Process
    cysteine biosynthetic process from serine
    Gene Properties
    Locus tag: PA0399
    Strand: +
    Entrez Gene ID: 878291
    Accession: NP_249090.1
    GI: 15595596
    Sequence start: 440638
    Sequence End: 442011
    Sequence Length: 1373
    Gene Sequence:
    >PA0399
    ATGACTTCCGACTCACGTCCCGCCGTGCTCGACCTGATCGGCAACACCCCGCTGGTTCGCGTGACGCGCTTCGATACCGGCCCCTGCACCCTGTACCTCAAGCTCGAATCGCAGAACCCCGGCGGCTCCATCAAGGATCGCATCGGTGTCGCCATGATCGAGGCCGCCGAGCGTGACGGCCGCCTGCGGCCCGGTGGCACCATCGTCGAGGCCACCGCCGGCAACACCGGTCTCGGCCTGGCCCTGGTCGGCCGCGCGAAGGGCTACCGGGTGGTGCTGGTGGTGCCGGACAAGATGTCCACCGAGAAGGTCCTGCACCTGCGCGCCATGGGCGCCGAGGTGCACATCACCCGATCGGACGTCGGCAAGGGCCATCCGGAGTACTACCAGGACGTTGCCGCGCGCCTGGCGCAGGATATTCCCGGCGCCTTCTTCGCCGACCAGTTCAACAACCCGGCCAACCCGCTGGCCCACGAGTGCGGCACCGGCCCGGAGCTCTGGGCGCAGACCGGCCACGATCTCGACGCCATCGTCGTCGGCGTCGGCTCCTCCGGTACCCTGACCGGCCTTACCCGGTTCTTCCAGAAGGTCCAGCCGGAGCTGGAGATGGTGCTCGCCGATCCCGAGGGCTCGATCATGGCCGAGTACTCCCGCTCCGGCACCCTGGGTACGCCGGGTTCCTGGGCGGTGGAGGGCATCGGCGAGGACTTCGTACCGGCCATCGCCGACCTCTCCAGCGTGCGCCATGCCTATTCCATCAGCGACGAGGAAAGCTTCGCCATGGCCCGCGAACTGTTGCGCGTCGAGGGCATTCCCGGCGGCTCCTCCACCGGCACCCTGCTGGCCGCGGCGCTGCGCTTCTGTCGCGAGCAGAAGGAGCCGAAGCGGGTGGTCAGCTTCGTCTGCGACACCGGCACCCGCTACCTGTCGAAGATCTACAACGACCAGTGGATGACCGACCAGGGCCTGCTGCAACGCAAGCACTACGGCGACCTGCGCGACATCATCGCGCGGCGCTTCGAGGAGGGCCGGGTGATCAGCGTCGGTCCGGACGACACCCTGCTCACCGCCTTCCAGCGCATGCGCCTGGCCGACGTTTCGCAATTGCCGGTGCTGGACGATGGAAAACTGGTCGGTGTGATCGACGAGTCGGATATCCTGCTCGGTGTCCACGCCGACGCGCCACGCTTCCGCGATGCGGTAAGCAGCGCGATGAACGCCGCGCCGGAGACCCTCGCGCCCGGCGCCAGCCTGGCCCAGTTGCAGGCGGTCCTGGACCGCGGCCTGGTGGCGATCGTTGCCGATGCCAGCGGCTTCCACGGCCTGATCACCCGTTTCGACCTGTTGAACCATTTGCGGAGAAAGCTCGCATGA
    Protein Properties
    Protein Residues: 457
    Protein Molecular Weight: 49.2 kDa
    Protein Theoretical pI: 5.48
    Hydropathicity (GRAVY score): -0.078
    Charge at pH 7 (predicted): -8.7
    Protein Sequence:
    >PA0399
    MTSDSRPAVLDLIGNTPLVRVTRFDTGPCTLYLKLESQNPGGSIKDRIGVAMIEAAERDGRLRPGGTIVEATAGNTGLGLALVGRAKGYRVVLVVPDKMSTEKVLHLRAMGAEVHITRSDVGKGHPEYYQDVAARLAQDIPGAFFADQFNNPANPLAHECGTGPELWAQTGHDLDAIVVGVGSSGTLTGLTRFFQKVQPELEMVLADPEGSIMAEYSRSGTLGTPGSWAVEGIGEDFVPAIADLSSVRHAYSISDEESFAMARELLRVEGIPGGSSTGTLLAAALRFCREQKEPKRVVSFVCDTGTRYLSKIYNDQWMTDQGLLQRKHYGDLRDIIARRFEEGRVISVGPDDTLLTAFQRMRLADVSQLPVLDDGKLVGVIDESDILLGVHADAPRFRDAVSSAMNAAPETLAPGASLAQLQAVLDRGLVAIVADASGFHGLITRFDLLNHLRRKLA
    References
    External Links:
    Resource Link
    Genome ID: PA0399
    Entrez Gene ID: 878291
    NCBI Protein ID: 15595596
    General Reference: PaperBLAST - Find papers about PA0399 and its homologs