Identification
Name: 3-guanidinopropionase proclavaminic acid amidino hydrolase, PAH; proclavaminate amidino hydrolase; AUH; agmatine ureohydrolase
Synonyms: Not Available
Gene Name: gpuA
Enzyme Class: Not Available
Biological Properties
General Function: Not Available
Specific Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines, metal ion binding
Cellular Location: Cytoplasmic
KEGG Pathways:
  • superpathway of L-arginine, putrescine, and 4-aminobutyrate degradation ARGDEG-PWY
  • superpathway of polyamine biosynthesis I POLYAMSYN-PWY
  • L-arginine degradation III (arginine decarboxylase/agmatinase pathway) PWY0-823
  • putrescine biosynthesis I PWY-40
    KEGG Reactions: Not Available
    SMPDB Reactions: Not Available
    PseudoCyc/BioCyc Reactions:
    Thumb
    4-guanidinobutanoate + H2O → urea + 4-aminobutanoate
    ReactionCard
    Thumb
    agmatine + H2O → urea + putrescine
    ReactionCard
    Complex Reactions: Not Available
    Transports: Not Available
    Metabolites: Not Available
    GO Classification:
    Function
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
    metal ion binding
    Gene Properties
    Locus tag: PA0288
    Strand: +
    Entrez Gene ID: 880781
    Accession: NP_248979.1
    GI: 15595485
    Sequence start: 323616
    Sequence End: 324572
    Sequence Length: 956
    Gene Sequence:
    >PA0288
    ATGTCGAACGACCATCCGCAGCCCCTCGACGCCGCCGAGATTCCCCGCTTCGCCGGTATCCCGACCTTCATGCGCCTGCCGGCGTTCACCGACCCGGCGGCGCTGCAGGTCGGCCTGATCGGCGTGCCCTGGGATGGCGGCACCACCAACCGCGCCGGTGCCCGCCATGGCCCGCGCGAGGTGCGCAACCTGTCCAGCCTGATGCGCAAGGTGCATCACGTCAGCCGCATCGCGCCCTACGACCTGGTGCGGGTCGGCGATCTCGGCGACGCGCCGGTGAATCCCATCGACCTGCTCGATTCGCTGCGCCGCATCGAAGGCTTCTATCGCCAGGTCCATGCCGCCGGTACCCTGCCGCTGTCGGTCGGTGGCGACCACCTGGTGACCCTGCCGATCTTTCGCGCCCTGGGTCGCGAGCGGCCGCTGGGCATGGTGCATTTCGATGCGCATTCCGATACCAACGACCGCTACTTCGGCGACAACCCCTACACCCACGGCACGCCATTCCGCCGAGCCATAGAGGAAGGCCTGCTCGATCCGCTGCGCACGGTGCAGATCGGCATCCGCGGCTCGGTGTATTCGCCGGACGACGACGCTTTCGCCCGCGAGTGCGGCATCCGCGTGATCCACATGGAGGAGTTCGTCGAACTGGGCGTCGAGGCGACCCTGGCCGAAGCGCGGCGGGTGGTGGGCGCCGGGCCGACCTATGTGAGTTTCGACGTCGACGTGCTCGACCCGGCCTTCGCGCCCGGCACCGGCACCCCGGAGATCGGCGGCATGACCAGCCTCCAGGCCCAGCAGCTGGTCCGCGGCCTGCGCGGGCTGGACCTGGTCGGCGCCGACGTGGTGGAAGTCTCGCCGCCGTTCGATGTCGGCGGCGCCACGGCGCTGGTGGGGGCGACCATGATGTTCGAGCTGCTCTGCCTGCTTGCCGAGTCGGCCGCGCGAAGCGCCTGA
    Protein Properties
    Protein Residues: 318
    Protein Molecular Weight: 34.2 kDa
    Protein Theoretical pI: 5.18
    Hydropathicity (GRAVY score): -0.013
    Charge at pH 7 (predicted): -9.65
    Protein Sequence:
    >PA0288
    MSNDHPQPLDAAEIPRFAGIPTFMRLPAFTDPAALQVGLIGVPWDGGTTNRAGARHGPREVRNLSSLMRKVHHVSRIAPYDLVRVGDLGDAPVNPIDLLDSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGRERPLGMVHFDAHSDTNDRYFGDNPYTHGTPFRRAIEEGLLDPLRTVQIGIRGSVYSPDDDAFARECGIRVIHMEEFVELGVEATLAEARRVVGAGPTYVSFDVDVLDPAFAPGTGTPEIGGMTSLQAQQLVRGLRGLDLVGADVVEVSPPFDVGGATALVGATMMFELLCLLAESAARSA
    References
    External Links:
    Resource Link
    Genome ID: PA0288
    Entrez Gene ID: 880781
    NCBI Protein ID: 15595485
    General Reference: PaperBLAST - Find papers about PA0288 and its homologs