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Record Information |
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| Version |
1.0 |
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| Update Date |
1/22/2018 12:54:54 PM |
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Metabolite ID | PAMDB110481 |
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Identification |
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| Name: |
dGTP |
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| Description: | A 2'-deoxyribonucleoside triphosphate oxoanion arising from global deprotonation of the triphosphate OH groups of 2'-deoxyguanosine 5'-triphosphate. |
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Structure |
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| Synonyms: | -
2'-deoxyguanosine-5'-triphosphate
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deoxy-GTP
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deoxyguanosine-triphosphate
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Chemical Formula: |
C10H12N5O13P3
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| Average Molecular Weight: |
503.15 |
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| Monoisotopic Molecular
Weight: |
506.9957451569 |
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| InChI Key: |
HAAZLUGHYHWQIW-KVQBGUIXSA-J |
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| InChI: |
InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/p-4/t4-,5+,6+/m0/s1 |
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| CAS
number: |
2564-35-4 |
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| IUPAC Name: | ({[({[(2R,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid |
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Traditional IUPAC Name: |
dGTP |
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| SMILES: | C(OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])C1(OC(CC(O)1)N3(C=NC2(C(=O)NC(N)=NC=23))) |
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Chemical Taxonomy |
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Taxonomy Description | This compound belongs to the class of chemical entities known as purine 2'-deoxyribonucleoside triphosphates. These are purine nucleotides with triphosphate group linked to the ribose moiety lacking a hydroxyl group at position 2. |
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Kingdom |
Chemical entities |
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| Super Class | Organic compounds |
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Class |
Nucleosides, nucleotides, and analogues |
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| Sub Class | Purine nucleotides |
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Direct Parent |
Purine 2'-deoxyribonucleoside triphosphates |
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| Alternative Parents |
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| Substituents |
- Purine 2'-deoxyribonucleoside triphosphate
- Imidazopyrimidine
- Purine
- Monoalkyl phosphate
- Hydroxypyrimidine
- N-substituted imidazole
- Organic phosphoric acid derivative
- Phosphoric acid ester
- Pyrimidine
- Alkyl phosphate
- Heteroaromatic compound
- Imidazole
- Azole
- Oxolane
- Secondary alcohol
- Oxacycle
- Azacycle
- Organoheterocyclic compound
- Hydrocarbon derivative
- Organooxygen compound
- Organonitrogen compound
- Alcohol
- Organic oxygen compound
- Organopnictogen compound
- Organic nitrogen compound
- Organic oxide
- Aromatic heteropolycyclic compound
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| Molecular Framework |
Aromatic heteropolycyclic compounds |
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| External Descriptors |
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Physical Properties |
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| State: |
Solid |
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| Charge: | -4 |
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Melting point: |
Not Available |
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| Experimental Properties: |
| Property | Value | Reference |
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| Melting Point | Not Available | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | Not Available | Not Available | | LogP | Not Available | Not Available |
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| Predicted Properties |
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Biological Properties |
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| Cellular Locations: |
Not Available |
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| Reactions: | |
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Pathways: |
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Spectra |
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| Spectra: |
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References |
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| References: |
- Yamaguchi T, Yamada R, Tomikawa A, Shudo K, Saito M, Ishikawa F, Saneyoshi M (2001)Inhibition of human telomerase by L-enantiomers of natural 2'-deoxyribonucleoside 5'-triphosphates. Nucleosides, nucleotides & nucleic acids 20, Pubmed: 11562994
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| Synthesis Reference: |
Not Available |
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| Material Safety Data Sheet (MSDS) |
Download (PDF) |
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Links |
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| External Links: |
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