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Record Information |
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| Version |
1.0 |
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| Update Date |
1/22/2018 11:54:54 AM |
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Metabolite ID | PAMDB100042 |
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Identification |
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| Name: |
furanomycin |
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| Description: | A non-proteinogenic L-α-amino acid that is L-alanine in which the methyl group is replaced by a (2R,5S)-5-methyl-2,5-dihydrofuran-2-yl moiety. |
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Structure |
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| Synonyms: | - (+)-furanomycin
- (2S,2'R,5'S)-2-amino-2-(5'-methyl-2',5'-dihydrofuran-2'-yl)acetic acid
- (6S)-
 2-6(8)7(9)10/h2-6H,8H2,1H3,(H,9,10)/t4-,5+,6-/m0/s1</td></tr><tr><th>CAS
number:</th><td>
<span class='wishart wishart-not-available'>Not Available</span></td></tr><tr><th>IUPAC Name:</th><td>(2<i>S</i>)-amino[(2<i>R</i>,5<i>S</i>)-5-methyl-2,5-dihydrofuran-2-yl]acetic acid</td></tr><tr><th>
Traditional IUPAC Name:</th><td>
<span class='wishart wishart-not-available'>Not Available</span></td></tr><tr><th>SMILES:</th><td>C[C@@H]1O[C@H](C=C1)[C@H](N)C(O)=O</td></tr><tr id=)
Chemical Taxonomy |
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Taxonomy Description | This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. |
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Kingdom |
Organic compounds |
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| Super Class | Organic acids and derivatives |
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Class |
Carboxylic acids and derivatives |
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| Sub Class | Amino acids, peptides, and analogues |
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Direct Parent |
L-alpha-amino acids |
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| Alternative Parents |
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| Substituents |
- L-alpha-amino acid
- Dihydrofuran
- Amino acid
- Carboxylic acid
- Dialkyl ether
- Ether
- Monocarboxylic acid or derivatives
- Oxacycle
- Organoheterocyclic compound
- Amine
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Hydrocarbon derivative
- Primary aliphatic amine
- Organic oxide
- Organopnictogen compound
- Organic oxygen compound
- Organic nitrogen compound
- Carbonyl group
- Aliphatic heteromonocyclic compound
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| Molecular Framework |
Aliphatic heteromonocyclic compounds |
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| External Descriptors |
- non-proteinogenic L-alpha-amino acid, dihydrofuran (CHEBI:79390)
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Physical Properties |
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| State: |
Not Available |
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| Charge: | 0 |
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Melting point: |
Not Available |
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| Experimental Properties: |
Not Available |
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| Predicted Properties |
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Biological Properties |
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| Cellular Locations: |
Not Available |
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| Reactions: | |
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Pathways: |
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Spectra |
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| Spectra: |
Not Available |
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References |
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| References: |
- Kohno T, Kohda D, Haruki M, Yokoyama S, Miyazawa T. Nonprotein amino acid
furanomycin, unlike isoleucine in chemical structure, is charged to isoleucine
tRNA by isoleucyl-tRNA synthetase and incorporated into protein. J Biol Chem.
1990 Apr 25;265(12):6931-5. Pubmed: 2182633
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| Synthesis Reference: |
Not Available |
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| Material Safety Data Sheet (MSDS) |
Not Available |
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Links |
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| External Links: |
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