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Record Information |
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| Version |
1.0 |
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| Update Date |
1/22/2018 12:54:54 PM |
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Metabolite ID | PAMDB003624 |
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Identification |
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| Name: |
8-oxo-dGMP |
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| Description: | 8-Oxo-dGMP is a metabolite of 8-oxo-dGTP which is a potent mutagenic substrate for DNA synthesis. 8-Oxo-dGTP is rapidly degraded to 8-oxo-dGMP by cellular 8-oxo-dGTPase activity. |
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Structure |
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| Synonyms: | - (2R,3S,5R)-5-(2-amino-6,8-dioxo-3,7-dihydropurin-9-yl)-3-hydroxyoxolan-2-ylmethyl dihydrogen phosphate
- (2R,3S,5R)-5-(2-amino-6,8-dioxo-3,7-Dihydropurin-9-yl)-3-hydroxyoxolan-2-ylmethyl dihydrogen phosphoric acid
- 2'-Deoxy-7,8-dihydro-8-oxo-5'-guanylate
- 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid
- 2'-deoxy-7,8-dihydro-8-oxoguanosine 5'-monophosphate
- 2'-Deoxy-7,8-dihydro-8-oxoguanosine 5'-monophosphoric acid
- 2'-Deoxy-8-oxo-7,8-dihydroguanosine 5'-(dihydrogen phosphate)
- 2'-Deoxy-8-oxo-7,8-dihydroguanosine 5'-(dihydrogen phosphoric acid)
- 8-hydroxydeoxyguanosine 5'-monophosphate
- 8-Hydroxydeoxyguanosine 5'-monophosphoric acid
- 8-OH-Dgmp
- 8-oxo-2'-deoxyguanosine-5'-monophosphate
- 8-oxo-2'-Deoxyguanosine-5'-monophosphoric acid
- 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate
- 8-oxo-7,8-dihydro-2'-Deoxyguanosine 5'-triphosphoric acid
- 8-Oxo-dGMP
- 8OG
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Chemical Formula: |
C10H14N5O8P |
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| Average Molecular Weight: |
363.2206 |
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| Monoisotopic Molecular
Weight: |
363.057998961 |
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| InChI Key: |
AQIVLFLYHYFRKU-VPENINKCSA-N |
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| InChI: | InChI=1S/C10H14N5O8P/c11-9-13-7-6(8(17)14-9)12-10(18)15(7)5-1-3(16)4(23-5)2-22-24(19,20)21/h3-5,16H,1-2H2,(H,12,18)(H2,19,20,21)(H3,11,13,14,17)/t3-,4+,5+/m0/s1 |
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| CAS
number: |
Not Available |
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| IUPAC Name: | {[(2R,3S,5R)-5-(6,8-dihydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid |
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Traditional IUPAC Name: |
[(2R,3S,5R)-5-(6,8-dihydroxy-2-imino-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxyphosphonic acid |
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| SMILES: | [H][C@]1(O)C[C@@]([H])(O[C@]1([H])COP(O)(O)=O)N1C(O)=NC2=C1NC(=N)N=C2O |
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Chemical Taxonomy |
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Taxonomy Description | This compound belongs to the class of organic compounds known as purine ribonucleoside monophosphates. These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached. |
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Kingdom |
Organic compounds |
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| Super Class | Nucleosides, nucleotides, and analogues |
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Class |
Purine nucleotides |
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| Sub Class | Purine ribonucleotides |
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Direct Parent |
Purine ribonucleoside monophosphates |
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| Alternative Parents |
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| Substituents |
- Purine ribonucleoside monophosphate
- Purine
- Imidazopyrimidine
- Hydroxypyrimidine
- Monoalkyl phosphate
- Alkyl phosphate
- Pyrimidine
- Phosphoric acid ester
- Organic phosphoric acid derivative
- Organic phosphate
- N-substituted imidazole
- Saccharide
- Heteroaromatic compound
- Oxolane
- Imidazole
- Azole
- Secondary alcohol
- Oxacycle
- Azacycle
- Organoheterocyclic compound
- Hydrocarbon derivative
- Organooxygen compound
- Organonitrogen compound
- Alcohol
- Aromatic heteropolycyclic compound
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| Molecular Framework |
Aromatic heteropolycyclic compounds |
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| External Descriptors |
- purine 2'-deoxyribonucleoside 5'-monophosphate (CHEBI:63223 )
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Physical Properties |
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| State: |
Solid |
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| Charge: | -3 |
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Melting point: |
Not Available |
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| Experimental Properties: |
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| Predicted Properties |
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Biological Properties |
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| Cellular Locations: |
Cytoplasm |
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| Reactions: | |
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Pathways: |
Not Available |
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Spectra |
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| Spectra: |
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References |
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| References: |
Not Available |
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| Synthesis Reference: |
Not Available |
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| Material Safety Data Sheet (MSDS) |
Not Available |
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Links |
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| External Links: |
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