Potassium (PAMDB000632)

IdentificationTaxonomyPhysical PropertiesBiological PropertiesSpectraConcentrationsLinksReferencesEnzymes Transporters
Proteins (3280)
Record Information
Version 1.0
Update Date 1/22/2018 11:54:54 AM
Metabolite IDPAMDB000632
Identification
Name: Potassium
Description:Potassium is an essential electrolyte and part of many minerals. Potassium ion is a major intracellular cation in bacteria, plants and animals. It is necessary for the function of all living cells. There are a number of of potassium transport systems that regulate the intracellular potassium concentration.
Structure
Thumb
🔍MOLSDFPDBSMILESInChIView Structure
Synonyms:
  • K+
  • Kalium
  • Potassium
  • Potassium (ion)
  • Potassium (K+)
  • Potassium cation
  • Potassium ion
  • Potassium ion (K+)
  • Potassium ion (K1+)
  • Potassium ion(+)
  • Potassium ion(1+)
  • Potassium monocation
  • Potassium(+)
  • Potassium(1+)
  • Potassium(1+) ion
  • Potassium(I) cation
Chemical Formula: K
Average Molecular Weight: 39.0983
Monoisotopic Molecular Weight: 38.963706861
InChI Key: NPYPAHLBTDXSSS-UHFFFAOYSA-N
InChI:InChI=1S/K/q+1
CAS number: 7440-09-7
IUPAC Name:potassium(1+) ion
Traditional IUPAC Name: potassium(1+) ion
SMILES:[K+]
Chemical Taxonomy
Taxonomy DescriptionThis compound belongs to the class of inorganic compounds known as homogeneous alkali metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a alkali metal atom.
Kingdom Inorganic compounds
Super ClassHomogeneous metal compounds
Class Homogeneous alkali metal compounds
Sub ClassNot Available
Direct Parent Homogeneous alkali metal compounds
Alternative Parents Not Available
Substituents
  • Homogeneous alkali metal
  • Acyclic compound
Molecular Framework Acyclic compounds
External Descriptors
Physical Properties
State: Solid
Charge:1
Melting point: 63.2 °C
Experimental Properties:
PropertyValueSource
Predicted Properties
PropertyValueSource
logP0.2ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations: Cytoplasm
Reactions:
Adenosine triphosphate + Water + Potassium > ADP + Hydrogen ion + Potassium + Phosphate
Adenosine triphosphate + Water + Potassium > ADP + Hydrogen ion + Potassium + Phosphate
-->
Pathways:
Spectra
Spectra:
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-000i-9000000000-560fc6f738e9570ec8a2View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-000i-9000000000-560fc6f738e9570ec8a2View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-000i-9000000000-560fc6f738e9570ec8a2View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-000i-9000000000-bcbe5ea7d5d32f6a9598View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-000i-9000000000-bcbe5ea7d5d32f6a9598View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-000i-9000000000-bcbe5ea7d5d32f6a9598View in MoNA
References
References:
  • Beede DK: Mineral and water nutrition. Vet Clin North Am Food Anim Pract. 1991 Jul;7(2):373-90. Pubmed: 1893277
  • Brooks G: Potassium additive algorithm for use in continuous renal replacement therapy. Nurs Crit Care. 2006 Nov-Dec;11(6):273-80. Pubmed: 17883675
  • Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., Tanabe, M. (2012). "KEGG for integration and interpretation of large-scale molecular data sets." Nucleic Acids Res 40:D109-D114. Pubmed: 22080510
  • Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. Pubmed: 21097882
  • Preuss HG: Diet, genetics and hypertension. J Am Coll Nutr. 1997 Aug;16(4):296-305. Pubmed: 9263178
  • Schaafsma A, de Vries PJ, Saris WH: Delay of natural bone loss by higher intakes of specific minerals and vitamins. Crit Rev Food Sci Nutr. 2001 May;41(4):225-49. Pubmed: 11401244
  • SCHULTZ, S. G., WILSON, N. L., EPSTEIN, W. (1962). "Cation transport in Escherichia coli. II. Intracellular chloride concentration." J Gen Physiol 46:159-166. Pubmed: 13909522
Synthesis Reference: Alberti, Augusto. Recovering potassium salts from the refuse liquor of the manufacture of tartaric acid. (1910), US 957295 19100510 CAN 4:13164 AN 1910:13164
Material Safety Data Sheet (MSDS) Download (PDF)
External Links:
ResourceLink
CHEBI ID26216
HMDB IDHMDB00586
Pubchem Compound ID813
Kegg IDC00238
ChemSpider ID791
WikipediaPotassium
BioCyc IDK+
EcoCyc IDK+
Ligand ExpoK

Enzymes

Protein Details
• Potassium-transporting ATPase A chain
General function:
Involved in potassium-transporting ATPase activity
Specific function:
One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
Gene Name:
kdpA
Locus Tag:
PA1633
Molecular weight:
59.9 kDa
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In).
Protein Details
• Potassium-transporting ATPase B chain
General function:
Involved in nucleotide binding
Specific function:
One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
Gene Name:
kdpB
Locus Tag:
PA1634
Molecular weight:
73 kDa
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In).
Protein Details
• Potassium-transporting ATPase C chain
General function:
Involved in potassium-transporting ATPase activity
Specific function:
One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
Gene Name:
kdpC
Locus Tag:
PA1635
Molecular weight:
19.3 kDa
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In).
Protein Details
• Protein kdpF
General function:
Not Available
Specific function:
Specific function unknown
Gene Name:
kdpF
Locus Tag:
PA1632
Molecular weight:
3.2 kDa

Transporters

Protein Details
• Potassium-transporting ATPase A chain
General function:
Involved in potassium-transporting ATPase activity
Specific function:
One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
Gene Name:
kdpA
Locus Tag:
PA1633
Molecular weight:
59.9 kDa
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In).
Protein Details
• Potassium-transporting ATPase B chain
General function:
Involved in nucleotide binding
Specific function:
One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
Gene Name:
kdpB
Locus Tag:
PA1634
Molecular weight:
73 kDa
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In).
Protein Details
• Potassium-transporting ATPase C chain
General function:
Involved in potassium-transporting ATPase activity
Specific function:
One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
Gene Name:
kdpC
Locus Tag:
PA1635
Molecular weight:
19.3 kDa
Reactions
ATP + H(2)O + K(+)(Out) = ADP + phosphate + K(+)(In).
Protein Details
• Low affinity potassium transport system protein kup
General function:
Involved in potassium ion transmembrane transporter activity
Specific function:
Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system). Can also transport cesium
Gene Name:
kup
Locus Tag:
PA0917
Molecular weight:
68.7 kDa
Protein Details
• Trk system potassium uptake protein trkA
General function:
Involved in cation transmembrane transporter activity
Specific function:
Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH
Gene Name:
trkA
Locus Tag:
PA0016
Molecular weight:
49.9 kDa
Protein Details
• Trk system potassium uptake protein trkH
General function:
Involved in cation transmembrane transporter activity
Specific function:
Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity
Gene Name:
trkH
Locus Tag:
PA3210
Molecular weight:
52.6 kDa
Protein Details
• Glutathione-regulated potassium-efflux system protein kefB
General function:
Involved in solute:hydrogen antiporter activity
Specific function:
Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport
Gene Name:
kefB
Locus Tag:
PA1207
Molecular weight:
66.3 kDa
Protein Details
• Protein kdpF
General function:
Not Available
Specific function:
Specific function unknown
Gene Name:
kdpF
Locus Tag:
PA1632
Molecular weight:
3.2 kDa